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PLECONARIL

Product Name
PLECONARIL
CAS No.
153168-05-9
Chemical Name
PLECONARIL
Synonyms
Picovir;VP 63843;Rimiducid;WIN 63843;PLECONARIL;Pleconarilis;Pleconaril-d4;PLECONARIL USP/EP/BP;Pleconaril VP-63843 Win-63843;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
CBNumber
CB8840318
Molecular Formula
C18H18F3N3O3
Formula Weight
381.35
MOL File
153168-05-9.mol
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PLECONARIL Property

Melting point:
61-62°
Boiling point:
481.2±55.0 °C(Predicted)
Density 
1.271
storage temp. 
room temp
solubility 
DMSO: ≥10mg/mL (warmed)
pka
-1.33±0.10(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0307
Product name
Pleconaril
Purity
≥98% (HPLC)
Packaging
10mg
Price
$215
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0307
Product name
Pleconaril
Purity
≥98% (HPLC)
Packaging
50mg
Price
$316
Updated
2024/03/01
Cayman Chemical
Product number
28461
Product name
Pleconaril
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
28461
Product name
Pleconaril
Packaging
100mg
Price
$662
Updated
2024/03/01
Cayman Chemical
Product number
28461
Product name
Pleconaril
Packaging
25mg
Price
$241
Updated
2024/03/01
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PLECONARIL Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Pleconaril has been used as a control or reference compound to assess the antiviral activities of the benzothiophene and other heteroaromatic derivatives against hRV-B14, hRV-A21 and hRV-A71.

Uses

Picornavirus replication inhibitor. Antiviral.

General Description

Pleconaril is a drug, that has antiviral activity.

Pharmaceutical Applications

An oxadiazole active against most enteroviruses and rhinoviruses. It binds to the hydrophobic pocket of the virus capsid protein VP1, inducing conformational changes that lead to altered receptor binding and viral uncoating. Concerns over safety and efficacy have constrained development of the drug.

Biochem/physiol Actions

Pleconaril is an effective drug against enteroviral infections. It can be used to treat chronic meningoencephalitis caused by echo virus 6.This can block viral replication by blocking the viral uncoating process and viral attachment to host cell receptors.

PLECONARIL Preparation Products And Raw materials

Raw materials

Preparation Products

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PLECONARIL Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58
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View Lastest Price from PLECONARIL manufacturers

Dideu Industries Group Limited
Product
PLECONARIL 153168-05-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-15
Career Henan Chemical Co
Product
PLECONARIL 153168-05-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
kg/T
Release date
2019-12-18

153168-05-9, PLECONARILRelated Search:


  • PLECONARIL
  • WIN 63843
  • 3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Picovir
  • 3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
  • 1,2,4-Oxadiazole,3-[3,5-diMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
  • VP 63843
  • 3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propoxy)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Rimiducid
  • Pleconarilis
  • 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Pleconaril-d4
  • PLECONARIL USP/EP/BP
  • Pleconaril VP-63843 Win-63843
  • 153168-05-9
  • Anti-virals
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API